Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Bromodomain-containing protein 4 [44-164]' and Ligand = 'BDBM425242'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Bromodomain-containing protein 4 [44-164] (Homo sapiens (Human))	BDBM425242 (4-[1-(2-fluorophenyl) sulfonyl-3-(1-methyl- pyrazo...) Show SMILES Cc1noc(C)c1-c1cnc2c(cn(c2c1)S(=O)(=O)c1ccccc1F)-c1cnn(C)c1 Show InChI InChI=1S/C22H18FN5O3S/c1-13-21(14(2)31-26-13)15-8-19-22(24-9-15)17(16-10-25-27(3)11-16)12-28(19)32(29,30)20-7-5-4-6-18(20)23/h4-12H,1-3H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Plexxikon Inc. US Patent					Assay Description Binding of compounds of formula (I) with bromodomain 2, 3 4 was assessed using Alphascreen binding assay. The inhibition of the interaction between b...				US Patent US10519177 (2019) BindingDB Entry DOI: 10.7270/Q2154KDK
					More data for this Ligand-Target Pair