Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Bromodomain-containing protein 4 [44-164]' and Ligand = 'BDBM425383'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Bromodomain-containing protein 4 [44-164] (Homo sapiens (Human))	BDBM425383 (2-[6-(3,5-dimethylisoxazol-4-yl)-1-(1- phenylethyl...) Show SMILES CC(c1ccccc1)n1cc(C#C[Si](C)(C)C)c2ncc(cc12)-c1c(C)noc1C Show InChI InChI=1S/C25H27N3OSi/c1-17-24(19(3)29-27-17)22-14-23-25(26-15-22)21(12-13-30(4,5)6)16-28(23)18(2)20-10-8-7-9-11-20/h7-11,14-16,18H,1-6H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Plexxikon Inc. US Patent					Assay Description Binding of compounds of formula (I) with bromodomain 2, 3 4 was assessed using Alphascreen binding assay. The inhibition of the interaction between b...				US Patent US10519177 (2019) BindingDB Entry DOI: 10.7270/Q2154KDK
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