Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Bromodomain-containing protein 4 [44-164]' and Ligand = 'BDBM425412'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Bromodomain-containing protein 4 [44-164] (Homo sapiens (Human))	BDBM425412 (4-[1-benzyl-3-[1-(2,2,2- trifluoroethyl)pyrazol-4-...) Show SMILES Cc1noc(C)c1-c1cnc2c(cn(Cc3ccccc3)c2c1)-c1cnn(CC(F)(F)F)c1 Show InChI InChI=1S/C24H20F3N5O/c1-15-22(16(2)33-30-15)18-8-21-23(28-9-18)20(13-31(21)11-17-6-4-3-5-7-17)19-10-29-32(12-19)14-24(25,26)27/h3-10,12-13H,11,14H2,1-2H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Plexxikon Inc. US Patent					Assay Description Binding of compounds of formula (I) with bromodomain 2, 3 4 was assessed using Alphascreen binding assay. The inhibition of the interaction between b...				US Patent US10519177 (2019) BindingDB Entry DOI: 10.7270/Q2154KDK
					More data for this Ligand-Target Pair