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Found 1 hit Enz. Inhib. hit(s) with Target = 'Bromodomain-containing protein 4 [44-168]/Histone H4' and Ligand = 'BDBM209494'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Bromodomain-containing protein 4 [44-168]/Histone H4


(Homo sapiens (Human))		BDBM209494
PNG
(US10328074, Example III-35 | US11077107, Example I...)
Show SMILES CC(C)Nc1nc(cn2c(C)nnc12)-c1nc2ccc(C)cc2n1Cc1ccccn1
Show InChI InChI=1S/C23H24N8/c1-14(2)25-21-23-29-28-16(4)30(23)13-19(26-21)22-27-18-9-8-15(3)11-20(18)31(22)12-17-7-5-6-10-24-17/h5-11,13-14H,12H2,1-4H3,(H,25,26)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 15n/an/an/an/an/an/a



Boehringer Ingelheim International GmbH

US Patent


Assay Description
Compounds are diluted in serial dilution 1:5 in assay buffer from 10 mM stock in DMSO (100 uM start concentration) in white OptiPlate-384 (PerkinElme...

US Patent US9266891 (2016)


BindingDB Entry DOI: 10.7270/Q23X85G7
More data for this
Ligand-Target Pair