BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Bromodomain-containing protein 4 [44-168]/Histone H4' and Ligand = 'BDBM209498'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Bromodomain-containing protein 4 [44-168]/Histone H4


(Homo sapiens (Human))		BDBM209498
PNG
(US10328074, Example III-39 | US11077107, Example I...)
Show SMILES COc1cc2n(Cc3ccccn3)c(nc2cn1)-c1cn2c(C)nnc2c(NC(C)C)n1
Show InChI InChI=1S/C22H23N9O/c1-13(2)25-20-22-29-28-14(3)30(22)12-17(26-20)21-27-16-10-24-19(32-4)9-18(16)31(21)11-15-7-5-6-8-23-15/h5-10,12-13H,11H2,1-4H3,(H,25,26)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 126n/an/an/an/an/an/a



Boehringer Ingelheim International GmbH

US Patent


Assay Description
Compounds are diluted in serial dilution 1:5 in assay buffer from 10 mM stock in DMSO (100 uM start concentration) in white OptiPlate-384 (PerkinElme...

US Patent US9266891 (2016)


BindingDB Entry DOI: 10.7270/Q23X85G7
More data for this
Ligand-Target Pair