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Found 1 hit Enz. Inhib. hit(s) with Target = 'Bromodomain-containing protein 4 [44-168]' and Ligand = 'BDBM215689'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Bromodomain-containing protein 4 [44-168]


(Homo sapiens (Human))		BDBM215689
PNG
(US9296748, I-25)
Show SMILES Cc1cc(cn(C)c1=O)-c1nc2ccc(cc2n1Cc1ccccn1)C1CCOCC1
Show InChI InChI=1S/C25H26N4O2/c1-17-13-20(15-28(2)25(17)30)24-27-22-7-6-19(18-8-11-31-12-9-18)14-23(22)29(24)16-21-5-3-4-10-26-21/h3-7,10,13-15,18H,8-9,11-12,16H2,1-2H3
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 72n/an/an/an/an/an/a



Boehringer Ingelheim International GmbH

US Patent


Assay Description
Compounds are diluted in serial dilution 1:5 in assay buffer from 10 mM stock in DMSO (100 μM start concentration) in white OptiPlate-384 (Perki...

US Patent US9296748 (2016)


BindingDB Entry DOI: 10.7270/Q21G0K4K
More data for this
Ligand-Target Pair