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Found 1 hit Enz. Inhib. hit(s) with Target = 'Bromodomain-containing protein 4 [44-168]' and Ligand = 'BDBM215695'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Bromodomain-containing protein 4 [44-168]


(Homo sapiens (Human))		BDBM215695
PNG
(US9296748, I-31)
Show SMILES COC[C@H](C)n1c(nc2ccc(cc12)N1CCOC[C@@H]1C)-c1cc(C)c(=O)n(C)c1 |r|
Show InChI InChI=1S/C23H30N4O3/c1-15-10-18(12-25(4)23(15)28)22-24-20-7-6-19(26-8-9-30-14-16(26)2)11-21(20)27(22)17(3)13-29-5/h6-7,10-12,16-17H,8-9,13-14H2,1-5H3/t16-,17-/m0/s1
PDB

UniProtKB/SwissProt

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PC cid
PC sid
UniChem
US Patent
n/an/a 75n/an/an/an/an/an/a



Boehringer Ingelheim International GmbH

US Patent


Assay Description
Compounds are diluted in serial dilution 1:5 in assay buffer from 10 mM stock in DMSO (100 μM start concentration) in white OptiPlate-384 (Perki...

US Patent US9296748 (2016)


BindingDB Entry DOI: 10.7270/Q21G0K4K
More data for this
Ligand-Target Pair