Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Bromodomain-containing protein 4 [44-168]' and Ligand = 'BDBM215741'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Bromodomain-containing protein 4 [44-168] (Homo sapiens (Human))	BDBM215741 (US9296748, II-28) Show SMILES Cc1cc(cn(C)c1=O)-c1nc2cnccc2n1Cc1ccccc1F Show InChI InChI=1S/C20H17FN4O/c1-13-9-15(11-24(2)20(13)26)19-23-17-10-22-8-7-18(17)25(19)12-14-5-3-4-6-16(14)21/h3-11H,12H2,1-2H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	128	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description Compounds are diluted in serial dilution 1:5 in assay buffer from 10 mM stock in DMSO (100 μM start concentration) in white OptiPlate-384 (Perki...				US Patent US9296748 (2016) BindingDB Entry DOI: 10.7270/Q21G0K4K
					More data for this Ligand-Target Pair