BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Bromodomain-containing protein 4 [44-168]' and Ligand = 'BDBM245785'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Bromodomain-containing protein 4 [44-168]


(Homo sapiens (Human))		BDBM245785
PNG
(US9428513, I-1)
Show SMILES COCCn1c(nc2cnc(cc12)N1CCOCC1)-c1cn2c(C)nnc2c(NC(C)C)n1
Show InChI InChI=1S/C22H29N9O2/c1-14(2)24-20-22-28-27-15(3)31(22)13-17(25-20)21-26-16-12-23-19(29-5-9-33-10-6-29)11-18(16)30(21)7-8-32-4/h11-14H,5-10H2,1-4H3,(H,24,25)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 32n/an/an/an/an/an/a



Boehringer Ingelheim International GmbH

US Patent


Assay Description
Compounds are diluted in serial dilution 1:5 in assay buffer from 10 mM stock in DMSO (100 μM start concentration) in white OptiPlate-384 (PerkinE...

US Patent US9428513 (2016)


BindingDB Entry DOI: 10.7270/Q23777MK
More data for this
Ligand-Target Pair