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Found 1 hit Enz. Inhib. hit(s) with Target = 'Bromodomain-containing protein 4 [44-477]' and Ligand = 'BDBM274321'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Bromodomain-containing protein 4 [44-477]


(Homo sapiens (Human))		BDBM274321
PNG
(6-(4-chlorophenyl)-3-cyclopropyl-5-(3,8-dimethyl-[...)
Show SMILES Cc1nnc2c(C)cc(cn12)N1C(c2c(C1=O)c(C1CC1)c(C)n2C)c1ccc(Cl)cc1
Show InChI InChI=1S/C25H24ClN5O/c1-13-11-19(12-30-15(3)27-28-24(13)30)31-22(17-7-9-18(26)10-8-17)23-21(25(31)32)20(16-5-6-16)14(2)29(23)4/h7-12,16,22H,5-6H2,1-4H3
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 12n/an/an/an/a7.5n/a



NOVARTIS AG

US Patent


Assay Description
All assays were performed in 384-well microtiter plates. Each assay plate contained 8-point serial dilutions for 40 test compounds, plus 16 high- and...

US Patent US9550796 (2017)


BindingDB Entry DOI: 10.7270/Q2QN68SK
More data for this
Ligand-Target Pair