Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'C-C chemokine receptor type 2' and Ligand = 'BDBM140239'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
C-C chemokine receptor type 2 (Homo sapiens (Human))	BDBM140239 (US8906911, 48) Show SMILES FC(F)(F)c1ccc(C#N)c(c1)N1C[C@@H]2C[C@H]1CN2C(=O)[C@@]12CCC[C@@H]1C[C@H](C2)N1CCC(CC1)c1ccccc1 |r| Show InChI InChI=1S/C33H37F3N4O/c34-33(35,36)26-9-8-24(19-37)30(16-26)39-20-29-17-28(39)21-40(29)31(41)32-12-4-7-25(32)15-27(18-32)38-13-10-23(11-14-38)22-5-2-1-3-6-22/h1-3,5-6,8-9,16,23,25,27-29H,4,7,10-15,17-18,20-21H2/t25-,27-,28+,29+,32-/m1/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	8	-43.0	51.8	n/a	n/a	n/a	n/a	7.4	4
AbbVie Inc. US Patent					Assay Description Radioligand binding assays were performed in CHO cells expressing human CCR2B and Galpha±16 coupling protein. All compounds were dissolved in DMSO a...				US Patent US8906911 (2014) BindingDB Entry DOI: 10.7270/Q2BV7FBV
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