Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'C-C chemokine receptor type 2' and Ligand = 'BDBM140256'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
C-C chemokine receptor type 2 (Homo sapiens (Human))	BDBM140256 (US8906911, 65) Show SMILES CC[C@@H]1COCC[C@@H]1N[C@@H]1C[C@H]2CCC[C@]2(C1)C(=O)N1C[C@@H]2C[C@H]1CN2c1cc(ccn1)C(F)(F)F |r| Show InChI InChI=1S/C27H37F3N4O2/c1-2-17-16-36-9-6-23(17)32-20-10-18-4-3-7-26(18,13-20)25(35)34-15-21-12-22(34)14-33(21)24-11-19(5-8-31-24)27(28,29)30/h5,8,11,17-18,20-23,32H,2-4,6-7,9-10,12-16H2,1H3/t17-,18-,20-,21+,22+,23+,26-/m1/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	6	-43.6	28	n/a	n/a	n/a	n/a	7.4	4
AbbVie Inc. US Patent					Assay Description Radioligand binding assays were performed in CHO cells expressing human CCR2B and Galpha±16 coupling protein. All compounds were dissolved in DMSO a...				US Patent US8906911 (2014) BindingDB Entry DOI: 10.7270/Q2BV7FBV
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