Compile Data Set for Download or QSAR

Found 3 hits Enz. Inhib. hit(s) with Target = 'C-C chemokine receptor type 2' and Ligand = 'BDBM50268423'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
C-C chemokine receptor type 2 (Homo sapiens (Human))	BDBM50268423 (CHEMBL497202 | N-(2-((1S,2R,4R)-4-(dimethylamino)-...) Show SMILES CSc1ccc(cc1)S(=O)(=O)C[C@@H]1C[C@@H](CC[C@@H]1NC(=O)CNC(=O)c1cccc(c1)C(F)(F)F)N(C)C |r| Show InChI InChI=1S/C26H32F3N3O4S2/c1-32(2)20-7-12-23(18(14-20)16-38(35,36)22-10-8-21(37-3)9-11-22)31-24(33)15-30-25(34)17-5-4-6-19(13-17)26(27,28)29/h4-6,8-11,13,18,20,23H,7,12,14-16H2,1-3H3,(H,30,34)(H,31,33)/t18-,20+,23-/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.300	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company Curated by ChEMBL					Assay Description Antagonist activity at CCR2 in human PBMC assessed as MCP1-induced calcium flux by fluorescence-imaging plate reader assay				Bioorg Med Chem Lett 19: 3418-22 (2009) Article DOI: 10.1016/j.bmcl.2009.05.041 BindingDB Entry DOI: 10.7270/Q27W6C3X
					More data for this Ligand-Target Pair
C-C chemokine receptor type 2 (Homo sapiens (Human))	BDBM50268423 (CHEMBL497202 | N-(2-((1S,2R,4R)-4-(dimethylamino)-...) Show SMILES CSc1ccc(cc1)S(=O)(=O)C[C@@H]1C[C@@H](CC[C@@H]1NC(=O)CNC(=O)c1cccc(c1)C(F)(F)F)N(C)C |r| Show InChI InChI=1S/C26H32F3N3O4S2/c1-32(2)20-7-12-23(18(14-20)16-38(35,36)22-10-8-21(37-3)9-11-22)31-24(33)15-30-25(34)17-5-4-6-19(13-17)26(27,28)29/h4-6,8-11,13,18,20,23H,7,12,14-16H2,1-3H3,(H,30,34)(H,31,33)/t18-,20+,23-/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.370	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company Curated by ChEMBL					Assay Description Displacement of [125I]MCP1 from CCR2 in human PBMC by millipore filter plate assay				Bioorg Med Chem Lett 19: 3418-22 (2009) Article DOI: 10.1016/j.bmcl.2009.05.041 BindingDB Entry DOI: 10.7270/Q27W6C3X
					More data for this Ligand-Target Pair
C-C chemokine receptor type 2 (Homo sapiens (Human))	BDBM50268423 (CHEMBL497202 | N-(2-((1S,2R,4R)-4-(dimethylamino)-...) Show SMILES CSc1ccc(cc1)S(=O)(=O)C[C@@H]1C[C@@H](CC[C@@H]1NC(=O)CNC(=O)c1cccc(c1)C(F)(F)F)N(C)C |r| Show InChI InChI=1S/C26H32F3N3O4S2/c1-32(2)20-7-12-23(18(14-20)16-38(35,36)22-10-8-21(37-3)9-11-22)31-24(33)15-30-25(34)17-5-4-6-19(13-17)26(27,28)29/h4-6,8-11,13,18,20,23H,7,12,14-16H2,1-3H3,(H,30,34)(H,31,33)/t18-,20+,23-/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.5	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company Curated by ChEMBL					Assay Description Antagonist activity at CCR2 in human PBMC assessed as MCP1-induced chemotaxis				Bioorg Med Chem Lett 19: 3418-22 (2009) Article DOI: 10.1016/j.bmcl.2009.05.041 BindingDB Entry DOI: 10.7270/Q27W6C3X
					More data for this Ligand-Target Pair