Compile Data Set for Download or QSAR

Found 3 hits Enz. Inhib. hit(s) with Target = 'C-C chemokine receptor type 3' and Ligand = 'BDBM50214121'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
C-C chemokine receptor type 3 (Homo sapiens (Human))	BDBM50214121 (4-(((4-chlorophenethyl)(1-(2,6-difluorobenzoyl)pip...) Show SMILES Cc1c(CN(CCc2ccc(Cl)cc2)C2CCN(CC2)C(=O)c2c(F)cccc2F)c(=O)n(-c2ccc(F)cc2)n1C Show InChI InChI=1S/C32H32ClF3N4O2/c1-21-27(31(41)40(37(21)2)26-12-10-24(34)11-13-26)20-39(17-14-22-6-8-23(33)9-7-22)25-15-18-38(19-16-25)32(42)30-28(35)4-3-5-29(30)36/h3-13,25H,14-20H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
UCB Pharma SA Curated by ChEMBL					Assay Description Antagonist activity at human CCR3 receptor assessed as inhibition of eotaxin-induced eosinophil shape change				Bioorg Med Chem Lett 17: 4228-31 (2007) Article DOI: 10.1016/j.bmcl.2007.05.035 BindingDB Entry DOI: 10.7270/Q2VQ32CH
					More data for this Ligand-Target Pair
C-C chemokine receptor type 3 (Homo sapiens (Human))	BDBM50214121 (4-(((4-chlorophenethyl)(1-(2,6-difluorobenzoyl)pip...) Show SMILES Cc1c(CN(CCc2ccc(Cl)cc2)C2CCN(CC2)C(=O)c2c(F)cccc2F)c(=O)n(-c2ccc(F)cc2)n1C Show InChI InChI=1S/C32H32ClF3N4O2/c1-21-27(31(41)40(37(21)2)26-12-10-24(34)11-13-26)20-39(17-14-22-6-8-23(33)9-7-22)25-15-18-38(19-16-25)32(42)30-28(35)4-3-5-29(30)36/h3-13,25H,14-20H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
UCB Pharma SA Curated by ChEMBL					Assay Description Antagonist activity at human CCR3 receptor assessed as inhibition of calcium flux				Bioorg Med Chem Lett 17: 4228-31 (2007) Article DOI: 10.1016/j.bmcl.2007.05.035 BindingDB Entry DOI: 10.7270/Q2VQ32CH
					More data for this Ligand-Target Pair
C-C chemokine receptor type 3 (Homo sapiens (Human))	BDBM50214121 (4-(((4-chlorophenethyl)(1-(2,6-difluorobenzoyl)pip...) Show SMILES Cc1c(CN(CCc2ccc(Cl)cc2)C2CCN(CC2)C(=O)c2c(F)cccc2F)c(=O)n(-c2ccc(F)cc2)n1C Show InChI InChI=1S/C32H32ClF3N4O2/c1-21-27(31(41)40(37(21)2)26-12-10-24(34)11-13-26)20-39(17-14-22-6-8-23(33)9-7-22)25-15-18-38(19-16-25)32(42)30-28(35)4-3-5-29(30)36/h3-13,25H,14-20H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
UCB Pharma SA Curated by ChEMBL					Assay Description Displacement of [125I]eotaxin from CCR3 receptor in human eosinophils				Bioorg Med Chem Lett 17: 4228-31 (2007) Article DOI: 10.1016/j.bmcl.2007.05.035 BindingDB Entry DOI: 10.7270/Q2VQ32CH
					More data for this Ligand-Target Pair