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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'C-C chemokine receptor type 3' and Ligand = 'BDBM50264210'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
C-C chemokine receptor type 3


(Homo sapiens (Human))		BDBM50264210
PNG
(2-(Azepan-1-ylcarbonyl)-N-{(3-exo)-8-[(6-fluoro-2-...)
Show SMILES Fc1ccc2cc(CN3[C@@H]4CC[C@@H]3CC(C4)NC(=O)c3ccccc3C(=O)N3CCCCCC3)ccc2c1 |r,TLB:7:8:14.15.13:10.11,THB:16:14:8:10.11|
Show InChI InChI=1S/C32H36FN3O2/c33-25-12-11-23-17-22(9-10-24(23)18-25)21-36-27-13-14-28(36)20-26(19-27)34-31(37)29-7-3-4-8-30(29)32(38)35-15-5-1-2-6-16-35/h3-4,7-12,17-18,26-28H,1-2,5-6,13-16,19-21H2,(H,34,37)/t27-,28-/m1/s1
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Article
PubMed
n/an/a 12n/an/an/an/an/an/a



Astellas Pharma. Inc.

Curated by ChEMBL


Assay Description
Antagonist activity at CCR3 receptor expressed in mouse B300-19 cells assessed as inhibition of eotaxin-induced calcium influx by spectrophotometry

Bioorg Med Chem 16: 8607-18 (2008)


Article DOI: 10.1016/j.bmc.2008.08.006
BindingDB Entry DOI: 10.7270/Q21J9BPZ
More data for this
Ligand-Target Pair