Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'C-C chemokine receptor type 4' and Ligand = 'BDBM374623'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
C-C chemokine receptor type 4 (Homo sapiens (Human))	BDBM374623 (1-(1-(2,4-Dichlorophenyl)ethyl)-6-(3′-methyl...) Show SMILES CC(c1ccc(Cl)cc1Cl)n1nc(C(N)=O)c2ncc(nc12)N1CCC(C(C)C1)N1CCCCC1 Show InChI InChI=1S/C25H31Cl2N7O/c1-15-14-33(11-8-20(15)32-9-4-3-5-10-32)21-13-29-23-22(24(28)35)31-34(25(23)30-21)16(2)18-7-6-17(26)12-19(18)27/h6-7,12-13,15-16,20H,3-5,8-11,14H2,1-2H3,(H2,28,35)	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	228	n/a	n/a	n/a	n/a	n/a	n/a
RAPT Therapeutics Curated by ChEMBL					Assay Description Antagonist activity at human CCR4 expressed in rat chem-5 cells assessed as inhibition of CCL22-induced calcium flux measured at 2.5 secs time interv...				J Med Chem 62: 6190-6213 (2019) Article DOI: 10.1021/acs.jmedchem.9b00506 BindingDB Entry DOI: 10.7270/Q2571GCP
					More data for this Ligand-Target Pair
C-C chemokine receptor type 4 (Homo sapiens (Human))	BDBM374623 (1-(1-(2,4-Dichlorophenyl)ethyl)-6-(3′-methyl...) Show SMILES CC(c1ccc(Cl)cc1Cl)n1nc(C(N)=O)c2ncc(nc12)N1CCC(C(C)C1)N1CCCCC1 Show InChI InChI=1S/C25H31Cl2N7O/c1-15-14-33(11-8-20(15)32-9-4-3-5-10-32)21-13-29-23-22(24(28)35)31-34(25(23)30-21)16(2)18-7-6-17(26)12-19(18)27/h6-7,12-13,15-16,20H,3-5,8-11,14H2,1-2H3,(H2,28,35)	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
St. Jude Research Hospital					Assay Description To measure binding of 125I-TARC or 125I-MDC to cells expressing CCR4 (e.g., CEM cells (e.g., ATCC HB-12624)), the 125I-TARC or 125I-MDC is diluted to...				J Med Chem 50: 1876-85 (2007) BindingDB Entry DOI: 10.7270/Q24F1T13
					More data for this Ligand-Target Pair