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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'C-C chemokine receptor type 4' and Ligand = 'BDBM374703'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
C-C chemokine receptor type 4


(Homo sapiens (Human))
BDBM374703
PNG
(1-((R)-1-(2,4-Dichlorophenyl)ethyl)-6-(4-((S)-2-(m...)
Show SMILES COC[C@@H]1CCCN1C1CC=C(CC1C)c1cnc2c(nn([C@H](C)c3ccc(Cl)cc3Cl)c2n1)C#N |r,c:11|
Show InChI InChI=1S/C27H30Cl2N6O/c1-16-11-18(6-9-25(16)34-10-4-5-20(34)15-36-3)24-14-31-26-23(13-30)33-35(27(26)32-24)17(2)21-8-7-19(28)12-22(21)29/h6-8,12,14,16-17,20,25H,4-5,9-11,15H2,1-3H3/t16?,17-,20+,25?/m1/s1
UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 300n/an/an/an/an/an/a



St. Jude Research Hospital



Assay Description
To measure binding of 125I-TARC or 125I-MDC to cells expressing CCR4 (e.g., CEM cells (e.g., ATCC HB-12624)), the 125I-TARC or 125I-MDC is diluted to...


J Med Chem 50: 1876-85 (2007)


BindingDB Entry DOI: 10.7270/Q24F1T13
More data for this
Ligand-Target Pair