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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'C-C chemokine receptor type 4' and Ligand = 'BDBM374710'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
C-C chemokine receptor type 4


(Homo sapiens (Human))		BDBM374710
PNG
(US10246462, Example 91)
Show SMILES CNC(=O)[C@@H]1CCCN1[C@H]1CC=C(C[C@H]1C)c1cnc2c(nn([C@H](C)c3ccc(Cl)cc3Cl)c2n1)C#N |r,c:12|
Show InChI InChI=1S/C27H29Cl2N7O/c1-15-11-17(6-9-23(15)35-10-4-5-24(35)27(37)31-3)22-14-32-25-21(13-30)34-36(26(25)33-22)16(2)19-8-7-18(28)12-20(19)29/h6-8,12,14-16,23-24H,4-5,9-11H2,1-3H3,(H,31,37)/t15-,16-,23+,24+/m1/s1
UniProtKB/SwissProt

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PC cid
PC sid
UniChem
US Patent
n/an/a 300n/an/an/an/an/an/a



St. Jude Research Hospital



Assay Description
To measure binding of 125I-TARC or 125I-MDC to cells expressing CCR4 (e.g., CEM cells (e.g., ATCC HB-12624)), the 125I-TARC or 125I-MDC is diluted to...

J Med Chem 50: 1876-85 (2007)


BindingDB Entry DOI: 10.7270/Q24F1T13
More data for this
Ligand-Target Pair