Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'C-C chemokine receptor type 5' and Ligand = 'BDBM50267126'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
C-C chemokine receptor type 5 (Homo sapiens (Human))	BDBM50267126 (CHEMBL4068906) Show SMILES [H][C@]12CCc3nnc(C)n3[C@@]1([H])CCN(CC[C@H](NC(=O)C1CCC(F)(F)CC1)c1ccccc1)C2 |r| Show InChI InChI=1S/C26H35F2N5O/c1-18-30-31-24-8-7-21-17-32(16-12-23(21)33(18)24)15-11-22(19-5-3-2-4-6-19)29-25(34)20-9-13-26(27,28)14-10-20/h2-6,20-23H,7-17H2,1H3,(H,29,34)/t21-,22+,23+/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	316	n/a	n/a	n/a	n/a	n/a
University Park Nottingham Curated by ChEMBL					Assay Description Antagonist activity at human CCR5 expressed in HEK 293 Glosensor cells assessed as reduction in RANTES-induced intracellular calcium levels preincuba...				J Med Chem 60: 1534-1554 (2017) Article DOI: 10.1021/acs.jmedchem.6b01801 BindingDB Entry DOI: 10.7270/Q2251MPR
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