Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'C-C chemokine receptor type 7' and Ligand = 'BDBM50463578'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
C-C chemokine receptor type 7 (Homo sapiens (Human))	BDBM50463578 (CHEMBL4250007) Show SMILES NC(=O)c1ccc(cc1)-c1ccc(cc1)S(=O)(=O)[C@H]1CC[C@@H](CC1)Nc1ccc(cn1)C(F)(F)F |r,wU:18.19,wD:21.26,(46,-48.4,;44.66,-49.17,;44.66,-50.71,;43.33,-48.4,;41.99,-49.17,;40.66,-48.4,;40.67,-46.86,;41.99,-46.09,;43.33,-46.86,;39.34,-46.09,;38,-46.86,;36.67,-46.08,;36.68,-44.54,;38,-43.78,;39.34,-44.54,;35.35,-43.77,;34.57,-42.43,;36.11,-42.43,;34.02,-44.54,;34.01,-46.08,;32.68,-46.84,;31.35,-46.07,;31.34,-44.53,;32.68,-43.77,;30.02,-46.84,;28.68,-46.07,;28.68,-44.52,;27.34,-43.76,;26.01,-44.53,;26.01,-46.07,;27.35,-46.84,;24.68,-43.76,;23.35,-44.53,;23.9,-42.42,;25.44,-42.42,)| Show InChI InChI=1S/C25H24F3N3O3S/c26-25(27,28)19-7-14-23(30-15-19)31-20-8-12-22(13-9-20)35(33,34)21-10-5-17(6-11-21)16-1-3-18(4-2-16)24(29)32/h1-7,10-11,14-15,20,22H,8-9,12-13H2,(H2,29,32)(H,30,31)/t20-,22-	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company Limited Curated by ChEMBL					Assay Description Inhibition of human CCR7 expressed in CHO cells assessed as decrease in CCL19-induced reduction of forskolin-stimulated cAMP accumulation preincubate...				Bioorg Med Chem Lett 28: 3067-3072 (2018) Article DOI: 10.1016/j.bmcl.2018.07.042 BindingDB Entry DOI: 10.7270/Q2DF6TWP
					More data for this Ligand-Target Pair