Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'C-X-C chemokine receptor type 2' and Ligand = 'BDBM50115226'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
C-X-C chemokine receptor type 2 (Homo sapiens (Human))	BDBM50115226 (CHEMBL3609019) Show SMILES OB(O)c1ccc(CN(Cc2ccccn2)c2ncc(cn2)C(=O)Nc2ccc(F)cc2)nc1 Show InChI InChI=1S/C23H20BFN6O3/c25-18-5-8-19(9-6-18)30-22(32)16-11-28-23(29-12-16)31(14-20-3-1-2-10-26-20)15-21-7-4-17(13-27-21)24(33)34/h1-13,33-34H,14-15H2,(H,30,32)	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.31E+3	n/a	n/a	n/a	n/a	n/a	n/a
Syntrix Biosystems Curated by ChEMBL					Assay Description Antagonist activity at CXCR2 (unknown origin) transfected in RBL cells assessed as inhibition of IL-8-mediated intracellular calcium release preincub...				Bioorg Med Chem Lett 25: 3793-7 (2015) Article DOI: 10.1016/j.bmcl.2015.07.090 BindingDB Entry DOI: 10.7270/Q2V989VF
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