Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
C-X-C chemokine receptor type 2 (Homo sapiens (Human)) | BDBM50177607 ((R)-2-(2-amino-5-(benzylthio)thiazolo[4,5-d]pyrimi...) | PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 160 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca Curated by ChEMBL | Assay Description Displacement of [125I]-IL8 from human CXCR2 transfected in HEK293 cells after 4 hrs by microbeta counting analysis | J Med Chem 56: 3177-90 (2013) Article DOI: 10.1021/jm3012273 BindingDB Entry DOI: 10.7270/Q2ST7R7X | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
C-X-C chemokine receptor type 2 (Homo sapiens (Human)) | BDBM50177607 ((R)-2-(2-amino-5-(benzylthio)thiazolo[4,5-d]pyrimi...) | PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 120 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca R&D Charnwood Curated by ChEMBL | Assay Description Displacement of [125I]IL8 from human recombinant CXCR2 expressed in HEK293 membranes by SPA | Bioorg Med Chem Lett 16: 960-3 (2006) Article DOI: 10.1016/j.bmcl.2005.10.091 BindingDB Entry DOI: 10.7270/Q2D79B09 | |||||||||||
More data for this Ligand-Target Pair |