Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'C-X-C chemokine receptor type 3/Guanine nucleotide-binding protein subunit alpha-15' and Ligand = 'BDBM208618'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
C-X-C chemokine receptor type 3/Guanine nucleotide-binding protein subunit alpha-15 (Homo sapiens (Human))	BDBM208618 (US9266876, 85) Show SMILES C[C@@H]1CN(CCN1C(=O)Cn1cnc2cccnc12)c1scnc1-c1nc2cc(C)ccc2[nH]1 Show InChI InChI=1S/C24H24N8OS/c1-15-5-6-17-19(10-15)29-22(28-17)21-24(34-14-27-21)30-8-9-32(16(2)11-30)20(33)12-31-13-26-18-4-3-7-25-23(18)31/h3-7,10,13-14,16H,8-9,11-12H2,1-2H3,(H,28,29)/t16-/m1/s1	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1	n/a	n/a	n/a	n/a	7.4	37
Actelion Pharmaceuticals Ltd. US Patent					Assay Description The bioactivity of compounds is tested in a fluorometric imaging plate reader (FLIPR: Molecular Devices) using engineered CHO-K1 cells expressing the...				US Patent US9266876 (2016) BindingDB Entry DOI: 10.7270/Q2DB80NB
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