Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'C-X-C chemokine receptor type 3/Guanine nucleotide-binding protein subunit alpha-15' and Ligand = 'BDBM208709'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
C-X-C chemokine receptor type 3/Guanine nucleotide-binding protein subunit alpha-15 (Homo sapiens (Human))	BDBM208709 (US9266876, 176) Show SMILES C[C@@H]1CN(CCN1C(=O)Cn1nccc1C)c1sc(nc1-c1nc2ccccc2[nH]1)C(F)(F)F Show InChI InChI=1S/C22H22F3N7OS/c1-13-7-8-26-32(13)12-17(33)31-10-9-30(11-14(31)2)20-18(29-21(34-20)22(23,24)25)19-27-15-5-3-4-6-16(15)28-19/h3-8,14H,9-12H2,1-2H3,(H,27,28)/t14-/m1/s1	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.100	n/a	n/a	n/a	n/a	7.4	37
Actelion Pharmaceuticals Ltd. US Patent					Assay Description The bioactivity of compounds is tested in a fluorometric imaging plate reader (FLIPR: Molecular Devices) using engineered CHO-K1 cells expressing the...				US Patent US9266876 (2016) BindingDB Entry DOI: 10.7270/Q2DB80NB
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