BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'C-X-C chemokine receptor type 4' and Ligand = 'BDBM50383299'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
C-X-C chemokine receptor type 4


(Homo sapiens (Human))		BDBM50383299
PNG
(CHEMBL2029609)
Show SMILES [#6]\[#6]-1=[#6]/[#6@H](-[#6]-[#6]-[#6]\[#7]=[#6](\[#7])-[#7])-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6]-[#6]\[#7]=[#6](\[#7])-[#7])-[#6](=O)-[#7]-[#6@@H](-[#6]-c2ccc3ccccc3c2)-[#6](=O)-[#7]-[#6]-[#6](=O)-[#7]-[#6@@H]1-[#6]-c1ccc(-[#8])cc1 |r,c:1|
Show InChI InChI=1S/C38H50N10O5/c1-23-18-28(8-4-16-43-37(39)40)34(51)47-30(9-5-17-44-38(41)42)36(53)48-32(21-25-10-13-26-6-2-3-7-27(26)19-25)35(52)45-22-33(50)46-31(23)20-24-11-14-29(49)15-12-24/h2-3,6-7,10-15,18-19,28,30-32,49H,4-5,8-9,16-17,20-22H2,1H3,(H,45,52)(H,46,50)(H,47,51)(H,48,53)(H4,39,40,43)(H4,41,42,44)/b23-18+/t28-,30-,31+,32-/m0/s1
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 500n/an/an/an/an/an/a



Kyoto University

Curated by ChEMBL


Assay Description
Displacement of [125I]SDF-1alpha from CXCR4 expressed in HEK293 cell membrane after 1 hr

J Med Chem 55: 2746-57 (2012)


Article DOI: 10.1021/jm2016914
BindingDB Entry DOI: 10.7270/Q2FJ2HTW
More data for this
Ligand-Target Pair