Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'COP9 signalosome complex subunit 5' and Ligand = 'BDBM401007'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
COP9 signalosome complex subunit 5 (Homo sapiens (Human))	BDBM401007 (US10005735, Compound 16) Show SMILES Sc1cccc2cc(cnc12)C(=O)NCc1ccccc1 Show InChI InChI=1S/C17H14N2OS/c20-17(19-10-12-5-2-1-3-6-12)14-9-13-7-4-8-15(21)16(13)18-11-14/h1-9,11,21H,10H2,(H,19,20)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research					Assay Description In brief, this Rpn11 bioassay employs a fluorescent polarization readout based on the ability of the 26S proteasome to cleave the protein substrate i...				Bioorg Med Chem 17: 8086-92 (2009) BindingDB Entry DOI: 10.7270/Q22R3V09
					More data for this Ligand-Target Pair