Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'CREB-binding protein' and Ligand = 'BDBM349502'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
CREB-binding protein (Homo sapiens (Human))	BDBM349502 ((R,S)-6-[7-(difluoromethyl)-3-methyl-6-(1-methylpy...) Show SMILES CN\C=C(/C=N)c1cc2C[C@@H](C)CN(c2cc1C(F)F)c1cccc2NC(=O)C[C@@H](C)Nc12 |r| Show InChI InChI=1S/C25H29F2N5O/c1-14-7-16-9-18(17(11-28)12-29-3)19(25(26)27)10-22(16)32(13-14)21-6-4-5-20-24(21)30-15(2)8-23(33)31-20/h4-6,9-12,14-15,25,28-30H,7-8,13H2,1-3H3,(H,31,33)/b17-12+,28-11?/t14-,15-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC. US Patent					Assay Description His/Flag epitope tagged CBP was cloned, expressed, and purified to homogeneity. CBP binding and inhibition was assessed by monitoring the engagement ...				US Patent US10206931 (2019) BindingDB Entry DOI: 10.7270/Q2GM89FR
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