Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Calcitonin gene-related peptide type 1 receptor/Receptor activity-modifying protein 1' and Ligand = 'BDBM50184067'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Calcitonin gene-related peptide type 1 receptor/Receptor activity-modifying protein 1 (Homo sapiens (Human))	BDBM50184067 ((S)-N-(1-methyl-2-oxo-5-phenyl-2,3-dihydro-1H-benz...) Show SMILES CN1c2ccccc2C(=N[C@H](NC(=O)N2CCC(CC2)N2Cc3ccccc3NC2=O)C1=O)c1ccccc1 |c:9| Show InChI InChI=1S/C30H30N6O3/c1-34-25-14-8-6-12-23(25)26(20-9-3-2-4-10-20)32-27(28(34)37)33-29(38)35-17-15-22(16-18-35)36-19-21-11-5-7-13-24(21)31-30(36)39/h2-14,22,27H,15-19H2,1H3,(H,31,39)(H,33,38)/t27-/m1/s1	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	8.40E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Department of Medicinal Chemistry Merck & Co. Curated by ChEMBL					Assay Description Displacement of [125I]CGRP from human cloned CLR/RAMP1 receptor expressed in E10 cells				Bioorg Med Chem Lett 16: 2595-8 (2006) Article DOI: 10.1016/j.bmcl.2006.02.051 BindingDB Entry DOI: 10.7270/Q2HT2NX8
					More data for this Ligand-Target Pair
Calcitonin gene-related peptide type 1 receptor/Receptor activity-modifying protein 1 (Homo sapiens (Human))	BDBM50184067 ((S)-N-(1-methyl-2-oxo-5-phenyl-2,3-dihydro-1H-benz...) Show SMILES CN1c2ccccc2C(=N[C@H](NC(=O)N2CCC(CC2)N2Cc3ccccc3NC2=O)C1=O)c1ccccc1 |c:9| Show InChI InChI=1S/C30H30N6O3/c1-34-25-14-8-6-12-23(25)26(20-9-3-2-4-10-20)32-27(28(34)37)33-29(38)35-17-15-22(16-18-35)36-19-21-11-5-7-13-24(21)31-30(36)39/h2-14,22,27H,15-19H2,1H3,(H,31,39)(H,33,38)/t27-/m1/s1	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.45E+3	n/a	n/a	n/a	n/a	n/a	n/a
Department of Medicinal Chemistry Merck & Co. Curated by ChEMBL					Assay Description Antagonist activity at human cloned CLR/RAMP1 receptor expressed in E10 cells measured as inhibition of CGRP-mediated cAMP production				Bioorg Med Chem Lett 16: 2595-8 (2006) Article DOI: 10.1016/j.bmcl.2006.02.051 BindingDB Entry DOI: 10.7270/Q2HT2NX8
					More data for this Ligand-Target Pair