Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Calcium/calmodulin-dependent protein kinase type II subunit delta' and Ligand = 'BDBM149453'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Calcium/calmodulin-dependent protein kinase type II subunit delta (Homo sapiens (Human))	BDBM149453 (US8975250, 60) Show SMILES CN(C)Cc1ccc(Nc2ncc3c(n2)n(CC(F)(F)F)c(N)c(C(N)=O)c3=O)cc1 Show InChI InChI=1S/C19H20F3N7O2/c1-28(2)8-10-3-5-11(6-4-10)26-18-25-7-12-14(30)13(16(24)31)15(23)29(17(12)27-18)9-19(20,21)22/h3-7H,8-9,23H2,1-2H3,(H2,24,31)(H,25,26,27)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	663	n/a	n/a	n/a	n/a	n/a	n/a
SANOFI US Patent					Assay Description The kinase activity of CaMKII beta is evaluated by means of a radioactive test on the recombinant CaMKII beta enzyme. The amount of ATP-gamma 33P in...				US Patent US8975250 (2015) BindingDB Entry DOI: 10.7270/Q2Z31XD8
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