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Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Calcium/calmodulin-dependent protein kinase type II subunit delta' and Ligand = 'BDBM292560'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Calcium/calmodulin-dependent protein kinase type II subunit delta


(Homo sapiens (Human))
BDBM292560
PNG
((S)-N-(2-(diethylamino)propyl)-2-(3-(hydroxymethyl...)
Show SMILES CCN(CC)[C@@H](C)CNC(=O)c1cc(nc(c1)-c1cnn2ccc(nc12)-c1cccs1)N1CC(CO)C1 |r|
Show InChI InChI=1S/C27H33N7O2S/c1-4-32(5-2)18(3)13-28-27(36)20-11-23(30-25(12-20)33-15-19(16-33)17-35)21-14-29-34-9-8-22(31-26(21)34)24-7-6-10-37-24/h6-12,14,18-19,35H,4-5,13,15-17H2,1-3H3,(H,28,36)/t18-/m0/s1
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 0.100n/an/an/an/an/an/a



Gilead Sciences, Inc.

US Patent


Assay Description
The biochemical activity of recombinant CaMKIIδ was measured by monitoring the phosphorylation of a target peptide using Homogenous Time Resolve...


US Patent US10100058 (2018)


BindingDB Entry DOI: 10.7270/Q2V98B4F
More data for this
Ligand-Target Pair
Calcium/calmodulin-dependent protein kinase type II subunit delta


(Homo sapiens (Human))
BDBM292560
PNG
((S)-N-(2-(diethylamino)propyl)-2-(3-(hydroxymethyl...)
Show SMILES CCN(CC)[C@@H](C)CNC(=O)c1cc(nc(c1)-c1cnn2ccc(nc12)-c1cccs1)N1CC(CO)C1 |r|
Show InChI InChI=1S/C27H33N7O2S/c1-4-32(5-2)18(3)13-28-27(36)20-11-23(30-25(12-20)33-15-19(16-33)17-35)21-14-29-34-9-8-22(31-26(21)34)24-7-6-10-37-24/h6-12,14,18-19,35H,4-5,13,15-17H2,1-3H3,(H,28,36)/t18-/m0/s1
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 21.6n/an/an/an/a



Gilead Sciences, Inc.

US Patent


Assay Description
CaMKII activity in neonatal rat ventricular myocytes (NRVM) was measured by monitoring the phosphorylation level of phospholamban using high-content ...


US Patent US10100058 (2018)


BindingDB Entry DOI: 10.7270/Q2V98B4F
More data for this
Ligand-Target Pair