Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Calcium release-activated calcium channel protein 1' and Ligand = 'BDBM141412'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Calcium release-activated calcium channel protein 1 (Homo sapiens (Human))	BDBM141412 (US10668051, Compound Example 56 | US8921364, 56) Show SMILES Cc1oncc1C(=O)Nc1ccc(cc1)-n1nc(cc1C1CC1)C(F)(F)F Show InChI InChI=1S/C18H15F3N4O2/c1-10-14(9-22-27-10)17(26)23-12-4-6-13(7-5-12)25-15(11-2-3-11)8-16(24-25)18(19,20)21/h4-9,11H,2-3H2,1H3,(H,23,26)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	63.2	n/a	n/a	n/a	n/a	n/a	n/a
RHIZEN PHARMACEUTICALS SA US Patent					Assay Description Inhibition of CRAC channels was determined following thapsigargin (Sigma, Cat #T9033) induced endoplasmic calcium release in Jurkat cells, (see Yasur...				US Patent US10668051 (2020) BindingDB Entry DOI: 10.7270/Q2V40Z7G
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