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Found 1 hit Enz. Inhib. hit(s) with Target = 'Calmodulin-domain protein kinase 1' and Ligand = 'BDBM50249998'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Calmodulin-domain protein kinase 1


(Toxoplasma gondii)		BDBM50249998
PNG
(CHEMBL4094646 | US11208411, Compound GXJ176)
Show SMILES Cc1cccc(Oc2nn(c3ncnc(N)c23)C(C)(C)C)c1
Show InChI InChI=1S/C16H19N5O/c1-10-6-5-7-11(8-10)22-15-12-13(17)18-9-19-14(12)21(20-15)16(2,3)4/h5-9H,1-4H3,(H2,17,18,19)
PDB

UniProtKB/TrEMBL

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Patents

Similars
Article
PubMed
n/an/a 14n/an/an/an/an/an/a



University of California

Curated by ChEMBL


Assay Description
Inhibition of C-terminal His-tagged full length Toxoplasma gondii CDPK1 expressed in Escherichia coli BL21 (DE3) using syntide-2 as substrate pre-inc...

J Med Chem 60: 9976-9989 (2017)


Article DOI: 10.1021/acs.jmedchem.7b01192
BindingDB Entry DOI: 10.7270/Q21G0PP0
More data for this
Ligand-Target Pair