Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Cannabinoid receptor 1 (Rattus norvegicus (rat)) | BDBM50582403 (CHEMBL5085420) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | MCE PC cid PC sid PDB UniChem | PDB Article PubMed | 0.390 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Displacement of [3H]CP55940 from rat brain membrane CB1 receptor assessed as inhibition constant incubated for 1 hr by TopCount scintillation countin... | Citation and Details Article DOI: 10.1021/acs.jmedchem.0c02053 BindingDB Entry DOI: 10.7270/Q2TB1BSB | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Cannabinoid receptor 1 (Homo sapiens (Human)) | BDBM50582403 (CHEMBL5085420) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | MCE PC cid PC sid PDB UniChem | PDB Article PubMed | n/a | n/a | n/a | n/a | 5.80 | n/a | n/a | n/a | n/a |
TBA | Assay Description Agonist activity at 3xHA tagged human CB1 receptor expressed in CHO-K1 cells assessed as reduction in forskolin-stimulated cAMP accumulation incubate... | Citation and Details Article DOI: 10.1021/acs.jmedchem.0c02053 BindingDB Entry DOI: 10.7270/Q2TB1BSB | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) |