Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Cannabinoid receptor 2 (Homo sapiens (Human)) | BDBM50248604 ((3',5'-dichloro-2,6-dihydroxybiphenyl-4-yl)(phenyl...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | US Patent | 2.94 | -49.5 | n/a | n/a | n/a | n/a | n/a | n/a | 30 |
The University of Tennessee Research Foundation US Patent | Assay Description Cell membranes from HEK293 cells transfected with the human CB1 receptor and membranes from CHO-K1 cells transfected with the human CB2 receptor were... | US Patent US9139546 (2015) BindingDB Entry DOI: 10.7270/Q2TQ609M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cannabinoid receptor 2 (Homo sapiens (Human)) | BDBM50248604 ((3',5'-dichloro-2,6-dihydroxybiphenyl-4-yl)(phenyl...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 2.94 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Tennessee-Memphis Curated by ChEMBL | Assay Description Binding affinity to human CB2 receptor transfected in HEK293 cells | Bioorg Med Chem Lett 19: 1691-3 (2009) Article DOI: 10.1016/j.bmcl.2009.01.100 BindingDB Entry DOI: 10.7270/Q2SX6D3N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cannabinoid receptor 2 (Homo sapiens (Human)) | BDBM50248604 ((3',5'-dichloro-2,6-dihydroxybiphenyl-4-yl)(phenyl...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 121 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Tennessee Health Science Center Curated by ChEMBL | Assay Description Displacement of [3H]-CP55940 from CB2 receptor (unknown origin) expressed in CHO cell membranes after 90 mins by liquid scintillation counting analys... | Bioorg Med Chem 23: 5390-401 (2015) Article DOI: 10.1016/j.bmc.2015.07.057 BindingDB Entry DOI: 10.7270/Q2HD7XF2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cannabinoid receptor 2 (Homo sapiens (Human)) | BDBM50248604 ((3',5'-dichloro-2,6-dihydroxybiphenyl-4-yl)(phenyl...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 121 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Displacement of [3H]-CP55940 from human recombinant cannabinoid CB2 receptor expressed in HEK cell membranes incubated for 1.5 hrs by liquid scintill... | Citation and Details Article DOI: 10.1016/j.bmc.2021.116035 BindingDB Entry DOI: 10.7270/Q2K077Z0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cannabinoid receptor 2 (Homo sapiens (Human)) | BDBM50248604 ((3',5'-dichloro-2,6-dihydroxybiphenyl-4-yl)(phenyl...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | n/a | 155 | n/a | n/a | n/a | n/a |
TBA | Assay Description Inverse agonist activity at cannabinoid CB2 receptor in human U2OS cells assessed as induction of beta-arrestin recruitment using CCF4/AM as substrat... | Citation and Details Article DOI: 10.1016/j.bmc.2021.116035 BindingDB Entry DOI: 10.7270/Q2K077Z0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cannabinoid receptor 2 (Homo sapiens (Human)) | BDBM50248604 ((3',5'-dichloro-2,6-dihydroxybiphenyl-4-yl)(phenyl...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | n/a | 155 | n/a | n/a | n/a | n/a |
TBA | Assay Description Inverse agonist activity at human recombinant cannabinoid CB2 receptor expressed in HEK cells transfected with CNG assessed as increase in cAMP level... | Citation and Details Article DOI: 10.1016/j.bmc.2021.116035 BindingDB Entry DOI: 10.7270/Q2K077Z0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cannabinoid receptor 2 (Homo sapiens (Human)) | BDBM50248604 ((3',5'-dichloro-2,6-dihydroxybiphenyl-4-yl)(phenyl...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | n/a | 153 | n/a | n/a | n/a | n/a |
University of Tennessee Health Science Center Curated by ChEMBL | Assay Description Inverse agonist activity at CB2 receptor (unknown origin) expressed in HEK cells assessed as increase in cAMP production measured at 50 mins by ACTOn... | Bioorg Med Chem 23: 5390-401 (2015) Article DOI: 10.1016/j.bmc.2015.07.057 BindingDB Entry DOI: 10.7270/Q2HD7XF2 | |||||||||||
More data for this Ligand-Target Pair |