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Compile Data Set for Download or QSAR

Found 3 hits Enz. Inhib. hit(s) with Target = 'Cannabinoid receptor 2' and Ligand = 'BDBM50272233'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Cannabinoid receptor 2


(Rattus norvegicus (Rat))
BDBM50272233
PNG
(CHEMBL501472 | N-(9-Ethyl-9H-carbazol-3-yl)-3-(3-(...)
Show SMILES CCn1c2ccccc2c2cc(NC(=O)CCc3nc(no3)-c3ccc(F)cc3C)ccc12
Show InChI InChI=1S/C26H23FN4O2/c1-3-31-22-7-5-4-6-20(22)21-15-18(9-11-23(21)31)28-24(32)12-13-25-29-26(30-33-25)19-10-8-17(27)14-16(19)2/h4-11,14-15H,3,12-13H2,1-2H3,(H,28,32)
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/an/an/a 0.270n/an/an/an/a



Amgen Inc.

Curated by ChEMBL


Assay Description
Agonist activity at rat recombinant CB2 receptor expressed in CHO-K1 cells assessed as inhibition of forskolin-stimulated intracellular cAMP level


J Med Chem 51: 5019-34 (2008)


Article DOI: 10.1021/jm800463f
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50272233
PNG
(CHEMBL501472 | N-(9-Ethyl-9H-carbazol-3-yl)-3-(3-(...)
Show SMILES CCn1c2ccccc2c2cc(NC(=O)CCc3nc(no3)-c3ccc(F)cc3C)ccc12
Show InChI InChI=1S/C26H23FN4O2/c1-3-31-22-7-5-4-6-20(22)21-15-18(9-11-23(21)31)28-24(32)12-13-25-29-26(30-33-25)19-10-8-17(27)14-16(19)2/h4-11,14-15H,3,12-13H2,1-2H3,(H,28,32)
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KEGG

UniProtKB/SwissProt

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antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/an/an/a 0.0890n/an/an/an/a



Amgen Inc.

Curated by ChEMBL


Assay Description
Agonist activity at human recombinant CB2 receptor expressed in Sf9 cells by GTP-europium binding assay


J Med Chem 51: 5019-34 (2008)


Article DOI: 10.1021/jm800463f
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50272233
PNG
(CHEMBL501472 | N-(9-Ethyl-9H-carbazol-3-yl)-3-(3-(...)
Show SMILES CCn1c2ccccc2c2cc(NC(=O)CCc3nc(no3)-c3ccc(F)cc3C)ccc12
Show InChI InChI=1S/C26H23FN4O2/c1-3-31-22-7-5-4-6-20(22)21-15-18(9-11-23(21)31)28-24(32)12-13-25-29-26(30-33-25)19-10-8-17(27)14-16(19)2/h4-11,14-15H,3,12-13H2,1-2H3,(H,28,32)
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/an/an/a 0.470n/an/an/an/a



Amgen Inc.

Curated by ChEMBL


Assay Description
Agonist activity at human recombinant CB2 receptor expressed in CHO-K1 cells assessed as inhibition of forskolin-stimulated intracellular cAMP level


J Med Chem 51: 5019-34 (2008)


Article DOI: 10.1021/jm800463f
More data for this
Ligand-Target Pair