BindingDB PrimarySearch

Found 2 hits Enz. Inhib. hit(s) with Target = 'Cannabinoid receptor 2' and Ligand = 'BDBM50541724'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Cannabinoid receptor 2 (Homo sapiens (Human))	BDBM50541724 (CHEMBL4640710) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	17	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Siena Curated by ChEMBL					Assay Description Displacement of [3H]-CP-55,940 from recombinant human CB2R expressed in HEK293 cell membranes				J Med Chem 63: 7369-7391 (2020) Article DOI: 10.1021/acs.jmedchem.0c00595 BindingDB Entry DOI: 10.7270/Q2N01B3C
University of Siena Curated by ChEMBL					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (Homo sapiens (Human))	BDBM50541724 (CHEMBL4640710) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	2.08E+3	n/a	n/a	n/a	n/a
University of Siena Curated by ChEMBL					Assay Description Inverse agonist activity at recombinant human CB2R expressed in CHOK1 cells assessed as increase in NKH477-stimulated intracellular cAMP levels after...				J Med Chem 63: 7369-7391 (2020) Article DOI: 10.1021/acs.jmedchem.0c00595 BindingDB Entry DOI: 10.7270/Q2N01B3C
University of Siena Curated by ChEMBL					More data for this Ligand-Target Pair