Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Carbonic anhydrase 2 (Homo sapiens (Human)) | BDBM50229543 (4-(benzylideneamino)benzenesulfonamide | 4-benzyli...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 21.4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
ENSCM-UMII-CNRS 5635 Curated by ChEMBL | Assay Description Inhibition of human carbonic anhydrase 2-catalyzed CO2 hydration by stopped flow technique | Bioorg Med Chem Lett 19: 6014-7 (2009) Article DOI: 10.1016/j.bmcl.2009.09.047 BindingDB Entry DOI: 10.7270/Q2FQ9WP1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Carbonic anhydrase 2 (Homo sapiens (Human)) | BDBM50229543 (4-(benzylideneamino)benzenesulfonamide | 4-benzyli...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 105 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
ENSCM/UMII/UMR-CNRS 5635 Curated by ChEMBL | Assay Description Inhibition of human carbonic anhydrase 2-catalyzed CO2 hydration preincubated for 10 mins by stopped-flow assay | Bioorg Med Chem 22: 2867-74 (2014) Article DOI: 10.1016/j.bmc.2014.03.041 BindingDB Entry DOI: 10.7270/Q27D2WPD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Carbonic anhydrase 2 (Homo sapiens (Human)) | BDBM50229543 (4-(benzylideneamino)benzenesulfonamide | 4-benzyli...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 289 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Harran University Curated by ChEMBL | Assay Description Inhibition of human recombinant carbonic anhydrase 2 preincubated for 15 mins by stopped-flow CO2 hydrase assay | Bioorg Med Chem 24: 982-8 (2016) Article DOI: 10.1016/j.bmc.2016.01.020 BindingDB Entry DOI: 10.7270/Q2KK9DNN | |||||||||||
More data for this Ligand-Target Pair |