Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Carbonic anhydrase 2 (Bos taurus) | BDBM81918 (p-Halide-sulfanilamide derivative, 2a) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase MCE PC cid PC sid PDB UniChem Patents Similars | Article PubMed | 14 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Tokushima Graduate School Curated by ChEMBL | Assay Description Binding affinity to bovine carbonic anhydrase 2 | Bioorg Med Chem Lett 21: 141-4 (2010) Article DOI: 10.1016/j.bmcl.2010.11.050 BindingDB Entry DOI: 10.7270/Q2K938T6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Carbonic anhydrase 2 (Bos taurus) | BDBM81918 (p-Halide-sulfanilamide derivative, 2a) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase MCE PC cid PC sid PDB UniChem Patents Similars | Article PubMed | 14 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Tokushima Graduate School Curated by ChEMBL | Assay Description Binding affinity to bovine carbonic anhydrase 2 | Bioorg Med Chem Lett 21: 141-4 (2010) Article DOI: 10.1016/j.bmcl.2010.11.050 BindingDB Entry DOI: 10.7270/Q2K938T6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Carbonic anhydrase 2 (Homo sapiens (Human)) | BDBM81918 (p-Halide-sulfanilamide derivative, 2a) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid PDB UniChem Patents Similars | Article PubMed | 81 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Union Life Sciences Ltd. Curated by ChEMBL | Assay Description Inhibition of human carbonic anhydrase 2 preincubated for 15 mins measured for 10 to 100 sec by stopped-flow method | J Med Chem 55: 3513-20 (2012) Article DOI: 10.1021/jm300203r BindingDB Entry DOI: 10.7270/Q2RX9D4X | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Carbonic anhydrase 2 (Homo sapiens (Human)) | BDBM81918 (p-Halide-sulfanilamide derivative, 2a) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid PDB UniChem Patents Similars | Article PubMed | 81 | -40.5 | n/a | n/a | n/a | n/a | n/a | 7.4 | 25 |
Universita degli Studi di Firenze | Assay Description Carbonic anhydrase (CA) inhibition against hCA II and V11 with synthesized compounds 2-8. | Chem Biol Drug Des 74: 196-202 (2009) Article DOI: 10.1111/j.1747-0285.2009.00842.x BindingDB Entry DOI: 10.7270/Q2G44NS1 | |||||||||||
More data for this Ligand-Target Pair |