BindingDB PrimarySearch

Found 2 hits Enz. Inhib. hit(s) with Target = 'Carboxypeptidase N catalytic chain' and Ligand = 'BDBM50275212'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Carboxypeptidase N catalytic chain (Homo sapiens (Human))	BDBM50275212 (CHEMBL4127473) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	>3.80E+5	n/a	n/a	n/a	n/a	n/a	n/a
Showa Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of human carboxypeptidase N preincubated for 10 mins followed by hippuryl-lysine substrate addition measured after 30 mins in absence of D...				Bioorg Med Chem Lett 28: 2256-2260 (2018) Article DOI: 10.1016/j.bmcl.2018.05.042 BindingDB Entry DOI: 10.7270/Q25M686N
Showa Pharmaceutical University Curated by ChEMBL					More data for this Ligand-Target Pair
Carboxypeptidase N catalytic chain (Homo sapiens (Human))	BDBM50275212 (CHEMBL4127473) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	>3.80E+5	n/a	n/a	n/a	n/a	n/a	n/a
Showa Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of human carboxypeptidase N preincubated for 10 mins followed by hippuryl-lysine substrate addition measured after 30 mins in presence of ...				Bioorg Med Chem Lett 28: 2256-2260 (2018) Article DOI: 10.1016/j.bmcl.2018.05.042 BindingDB Entry DOI: 10.7270/Q25M686N
Showa Pharmaceutical University Curated by ChEMBL					More data for this Ligand-Target Pair