Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Casein kinase I isoform delta' and Ligand = 'BDBM274745'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Casein kinase I isoform delta (Homo sapiens (Human))	BDBM274745 (6-fluoro-N-(6-(4-(4-fluoro- phenyl)-1,2-dimethyl-1...) Show SMILES Cc1nc(c(-c2ccc3nc(NC(=O)c4ccc(F)nc4)cn3n2)n1C)-c1ccc(F)cc1 Show InChI InChI=1S/C23H17F2N7O/c1-13-27-21(14-3-6-16(24)7-4-14)22(31(13)2)17-8-10-20-28-19(12-32(20)30-17)29-23(33)15-5-9-18(25)26-11-15/h3-12H,1-2H3,(H,29,33)	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.152	n/a	n/a	n/a	n/a	7.4	25
Bristol-Myers Squibb Company US Patent					Assay Description The kinase assay was performed in V-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme, subst...				US Patent US9556179 (2017) BindingDB Entry DOI: 10.7270/Q2G73GR5
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