Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Casein kinase I isoform delta' and Ligand = 'BDBM274746'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Casein kinase I isoform delta (Homo sapiens (Human))	BDBM274746 (N-(6-(4-(4-fluorophenyl)-1,2- dimethyl-1H-imidazol...) Show SMILES Cc1nc(c(-c2ccc3nc(NC(=O)c4ccc(O)nc4)cn3n2)n1C)-c1ccc(F)cc1 Show InChI InChI=1S/C23H18FN7O2/c1-13-26-21(14-3-6-16(24)7-4-14)22(30(13)2)17-8-9-19-27-18(12-31(19)29-17)28-23(33)15-5-10-20(32)25-11-15/h3-12H,1-2H3,(H,25,32)(H,28,33)	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.473	n/a	n/a	n/a	n/a	7.4	25
Bristol-Myers Squibb Company US Patent					Assay Description The kinase assay was performed in V-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme, subst...				US Patent US9556179 (2017) BindingDB Entry DOI: 10.7270/Q2G73GR5
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