BindingDB PrimarySearch

Found 2 hits Enz. Inhib. hit(s) with Target = 'Casein kinase II subunit alpha' and Ligand = 'BDBM11313'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Casein kinase II subunit alpha (Zea mays (Maize))	BDBM11313 (1,8-dihydroxy-4-nitro-anthraquinone \| 4,5-dihydrox...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	DrugBank MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank MMDB PDB Article PubMed	780	-34.5	n/a	n/a	n/a	n/a	n/a	7.5	22
University of Padova					Assay Description In vitro kinase assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of 100 uM ATP/ [gam...				J Biol Chem 278: 1831-6 (2003) Article DOI: 10.1074/jbc.M209367200 BindingDB Entry DOI: 10.7270/Q2GH9G5K
University of Padova					More data for this Ligand-Target Pair				3D Structure (crystal)
Casein kinase II subunit alpha (Homo sapiens (Human))	BDBM11313 (1,8-dihydroxy-4-nitro-anthraquinone \| 4,5-dihydrox...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	DrugBank MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	800	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
China Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of CK2alpha (unknown origin)				Eur J Med Chem 181: (2019) Article DOI: 10.1016/j.ejmech.2019.111581 BindingDB Entry DOI: 10.7270/Q29K4FJB
China Pharmaceutical University Curated by ChEMBL					More data for this Ligand-Target Pair