Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Casein kinase II subunit alpha (Homo sapiens (Human)) | BDBM50252622 (CHEMBL4070389) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid PDB UniChem | PDB Article PubMed | n/a | n/a | 370 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of recombinant human CK2alpha (1 to 336 residues) expressed in Escherichia coli BL21 (DE3) using RRADDSDDDD as substrate incubated for 10 ... | Citation and Details Article DOI: 10.1016/j.ejmech.2020.112267 BindingDB Entry DOI: 10.7270/Q2M330H3 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Casein kinase II subunit alpha (Homo sapiens (Human)) | BDBM50252622 (CHEMBL4070389) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid PDB UniChem | PDB Article PubMed | n/a | n/a | 370 | n/a | n/a | n/a | n/a | n/a | n/a |
Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge CB2 1EW, UK. Curated by ChEMBL | Assay Description Inhibition of CK2alpha (unknown origin) using RRRADDSDDDD as substrate after 40 mins by ADP-Glo assay | Bioorg Med Chem 25: 3471-3482 (2017) Article DOI: 10.1016/j.bmc.2017.04.037 BindingDB Entry DOI: 10.7270/Q29G5Q8D | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Casein kinase II subunit alpha (Homo sapiens (Human)) | BDBM50252622 (CHEMBL4070389) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid PDB UniChem | PDB Article PubMed | n/a | n/a | 370 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00063 BindingDB Entry DOI: 10.7270/Q2ZP4B53 | ||||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Casein kinase II subunit alpha (Homo sapiens (Human)) | BDBM50252622 (CHEMBL4070389) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid PDB UniChem | PDB Article PubMed | n/a | n/a | n/a | 320 | n/a | n/a | n/a | n/a | n/a |
Astex Pharmaceuticals , 436 Cambridge Science Park, Milton Road , Cambridge CB4 0QA , United Kingdom. Curated by ChEMBL | Assay Description Binding affinity to human CK2alpha expressed in Escherichia coli BL21(DE3) | J Med Chem 61: 1774-1784 (2018) Article DOI: 10.1021/acs.jmedchem.7b01298 BindingDB Entry DOI: 10.7270/Q26D5WGJ | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Casein kinase II subunit alpha (Homo sapiens (Human)) | BDBM50252622 (CHEMBL4070389) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid PDB UniChem | PDB Article PubMed | n/a | n/a | n/a | 320 | n/a | n/a | n/a | n/a | n/a |
Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge CB2 1EW, UK. Curated by ChEMBL | Assay Description Binding affinity to CK2alpha (unknown origin) by ITC | Bioorg Med Chem 25: 3471-3482 (2017) Article DOI: 10.1016/j.bmc.2017.04.037 BindingDB Entry DOI: 10.7270/Q29G5Q8D | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) |