BindingDB PrimarySearch

Found 2 hits Enz. Inhib. hit(s) with Target = 'Caspase-3' and Ligand = 'BDBM228619'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Caspase-3 (Homo sapiens (Human))	BDBM228619 (US9345789, Z-DEVD-FMK) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE KEGG PC cid PC sid UniChem	US Patent	n/a	n/a	130	n/a	n/a	n/a	n/a	5.8	n/a
The Board of Trustees of the Leland Stanford Junior University US Patent					Assay Description Assay buffers consist of 20 mM citric acid, 60 mM disodium hydrogen orthophosphate, 1 mM EDTA, 0.1% CHAPS, 4 mM DTT, pH 5.8 for legumain, 50 mM dihyd...				US Patent US9345789 (2016) BindingDB Entry DOI: 10.7270/Q2610Z63
					More data for this Ligand-Target Pair
Caspase-3 (Mus musculus)	BDBM228619 (US9345789, Z-DEVD-FMK) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase MCE KEGG PC cid PC sid UniChem	Article PubMed	n/a	n/a	130	n/a	n/a	n/a	n/a	7.4	25
Stanford University					Assay Description IC50 measurements and enzyme kinetics assays were performed on a Spectramax M5 fluorescent plate reader (Molecular Devices).				ACS Chem Biol 5: 233-43 (2010) Article DOI: 10.1021/cb900232a BindingDB Entry DOI: 10.7270/Q2Z31X0W
Stanford University					More data for this Ligand-Target Pair