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Found 1 hit Enz. Inhib. hit(s) with Target = 'Catechol O-methyltransferase' and Ligand = 'BDBM50058814'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Catechol O-methyltransferase


(Sus scrofa)		BDBM50058814
PNG
(CHEMBL63052 | N,N'-1,3-Propanediylbis(3,4-dihydrox...)
Show SMILES Oc1ccc(cc1O)C(=O)NCCCNC(=O)c1ccc(O)c(O)c1
Show InChI InChI=1S/C17H18N2O6/c20-12-4-2-10(8-14(12)22)16(24)18-6-1-7-19-17(25)11-3-5-13(21)15(23)9-11/h2-5,8-9,20-23H,1,6-7H2,(H,18,24)(H,19,25)
MMDB

UniProtKB/SwissProt

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PC cid
PC sid
UniChem

Patents

Similars
Article
PubMed
 300n/an/an/an/an/an/an/an/a



University of Otago

Curated by ChEMBL


Assay Description
In vitro inhibitory activity against Catechol-O-methyltransferase from porcine liver; Competitive mode of inhibition

J Med Chem 40: 2035-9 (1997)


Article DOI: 10.1021/jm9605187
BindingDB Entry DOI: 10.7270/Q27M072S
More data for this
Ligand-Target Pair