Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Catenin beta-1' and Ligand = 'BDBM50509786'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Catenin beta-1 (Homo sapiens (Human))	BDBM50509786 (CHEMBL4577989) Show SMILES NC(=O)C[C@H](NC(=O)[C@H](Cc1ccc2ccccc2c1)NC(=O)c1cc2cc(Cl)ccc2[nH]1)C(=O)N[C@@H](Cc1nn[nH]n1)C(=O)Nc1ccc(OC(F)(F)F)cc1 |r| Show InChI InChI=1S/C37H32ClF3N10O6/c38-23-7-12-26-22(15-23)16-28(44-26)35(55)45-27(14-19-5-6-20-3-1-2-4-21(20)13-19)34(54)46-29(17-31(42)52)36(56)47-30(18-32-48-50-51-49-32)33(53)43-24-8-10-25(11-9-24)57-37(39,40)41/h1-13,15-16,27,29-30,44H,14,17-18H2,(H2,42,52)(H,43,53)(H,45,55)(H,46,54)(H,47,56)(H,48,49,50,51)/t27-,29-,30-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	4.90E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
H. Lee Moffitt Cancer Center and Research Institute Curated by ChEMBL					Assay Description Inhibition of C-terminal fluorescein-labeled human TCF4 (7 to 51 residues) binding to wild-type C-terminal His6-tagged beta-catenin (138 to 781 resid...				J Med Chem 62: 3617-3635 (2019) Article DOI: 10.1021/acs.jmedchem.9b00147 BindingDB Entry DOI: 10.7270/Q2KP85G5
					More data for this Ligand-Target Pair
Catenin beta-1 (Homo sapiens (Human))	BDBM50509786 (CHEMBL4577989) Show SMILES NC(=O)C[C@H](NC(=O)[C@H](Cc1ccc2ccccc2c1)NC(=O)c1cc2cc(Cl)ccc2[nH]1)C(=O)N[C@@H](Cc1nn[nH]n1)C(=O)Nc1ccc(OC(F)(F)F)cc1 |r| Show InChI InChI=1S/C37H32ClF3N10O6/c38-23-7-12-26-22(15-23)16-28(44-26)35(55)45-27(14-19-5-6-20-3-1-2-4-21(20)13-19)34(54)46-29(17-31(42)52)36(56)47-30(18-32-48-50-51-49-32)33(53)43-24-8-10-25(11-9-24)57-37(39,40)41/h1-13,15-16,27,29-30,44H,14,17-18H2,(H2,42,52)(H,43,53)(H,45,55)(H,46,54)(H,47,56)(H,48,49,50,51)/t27-,29-,30-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.90E+4	n/a	n/a	n/a	n/a	n/a	n/a
H. Lee Moffitt Cancer Center and Research Institute Curated by ChEMBL					Assay Description Inhibition of C-terminal fluorescein-labeled human TCF4 (7 to 51 residues) binding to wild-type C-terminal His6-tagged beta-catenin (138 to 781 resid...				J Med Chem 62: 3617-3635 (2019) Article DOI: 10.1021/acs.jmedchem.9b00147 BindingDB Entry DOI: 10.7270/Q2KP85G5
					More data for this Ligand-Target Pair