BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Cathepsin B' and Ligand = 'BDBM50249607'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Cathepsin B


(Homo sapiens (Human))		BDBM50249607
PNG
(3-acetyl-5,8-dichloro-2-(2,4-dichlorophenylamino)q...)
Show SMILES CC(=O)c1c(Nc2ccc(Cl)cc2Cl)nc2c(Cl)ccc(Cl)c2c1O
Show InChI InChI=1S/C17H10Cl4N2O2/c1-7(24)13-16(25)14-9(19)3-4-10(20)15(14)23-17(13)22-12-5-2-8(18)6-11(12)21/h2-6H,1H3,(H2,22,23,25)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 3.89E+3n/an/an/an/an/an/a



Ewha Womans University

Curated by ChEMBL


Assay Description
Inhibition of human liver cathepsin B after 30 mins by fluorometric end-point assay

J Med Chem 52: 3093-7 (2009)


Article DOI: 10.1021/jm8014734
BindingDB Entry DOI: 10.7270/Q2KK9CQ4
More data for this
Ligand-Target Pair