Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Cathepsin D (Homo sapiens (Human)) | BDBM50099378 (CHEMBL3344165) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 447 | n/a | n/a | n/a | n/a | n/a | n/a |
The Walter and Eliza Hall Institute of Medical Research Curated by ChEMBL | Assay Description Inhibition of human cathepsin D assessed as cleavage of wtKAHRP fluorogenic substrate | J Med Chem 57: 7644-62 (2014) Article DOI: 10.1021/jm500797g BindingDB Entry DOI: 10.7270/Q2CR5W42 | |||||||||||
More data for this Ligand-Target Pair |