Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Cathepsin K' and Ligand = 'BDBM139527'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cathepsin K (Homo sapiens (Human))	BDBM139527 (US8889708, 26) Show SMILES COCCN1C(=O)Cc2ccc(cc12)-c1ccc(C[C@H](NC(=O)C23CCC(CC2)CN3)C#N)c(F)c1 |r| Show InChI InChI=1S/C28H31FN4O3/c1-36-11-10-33-25-14-20(3-5-22(25)15-26(33)34)19-2-4-21(24(29)13-19)12-23(16-30)32-27(35)28-8-6-18(7-9-28)17-31-28/h2-5,13-14,18,23,31H,6-12,15,17H2,1H3,(H,32,35)/t18?,23-,28?/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a	n/a	25
Boehringer Ingelheim International GmbH US Patent					Assay Description The recombinant human DPPI was diluted in TAGZyme buffer to 1 U/ml (38.1 ug/ml, respectively), and then activated by mixing in a 1:2 ratio with a Cys...				US Patent US8889708 (2014) BindingDB Entry DOI: 10.7270/Q2JM28BB
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