Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Cathepsin K' and Ligand = 'BDBM50390391'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cathepsin K (Homo sapiens (Human))	BDBM50390391 (CHEMBL2070937) Show SMILES O=C(NC1(CC1)C#N)[C@@H]1CCCC[C@H]1C(=O)N1CCN(CC1)c1nc2ccccc2s1 |r| Show InChI InChI=1S/C23H27N5O2S/c24-15-23(9-10-23)26-20(29)16-5-1-2-6-17(16)21(30)27-11-13-28(14-12-27)22-25-18-7-3-4-8-19(18)31-22/h3-4,7-8,16-17H,1-2,5-6,9-14H2,(H,26,29)/t16-,17-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of human recombinant cathepsin K using Z-Phe-Arg-AMC as substrate preincubated for 30 mins measured after 1 hr by quenched fluorescent res...				Bioorg Med Chem Lett 22: 5563-8 (2012) Article DOI: 10.1016/j.bmcl.2012.07.012 BindingDB Entry DOI: 10.7270/Q2DF6S86
					More data for this Ligand-Target Pair
Cathepsin K (Canis familiaris)	BDBM50390391 (CHEMBL2070937) Show SMILES O=C(NC1(CC1)C#N)[C@@H]1CCCC[C@H]1C(=O)N1CCN(CC1)c1nc2ccccc2s1 |r| Show InChI InChI=1S/C23H27N5O2S/c24-15-23(9-10-23)26-20(29)16-5-1-2-6-17(16)21(30)27-11-13-28(14-12-27)22-25-18-7-3-4-8-19(18)31-22/h3-4,7-8,16-17H,1-2,5-6,9-14H2,(H,26,29)/t16-,17-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of dog recombinant cathepsin K using Z-Phe-Arg-AMC as substrate preincubated for 30 mins measured after 1 hr by quenched fluorescent reson...				Bioorg Med Chem Lett 22: 5563-8 (2012) Article DOI: 10.1016/j.bmcl.2012.07.012 BindingDB Entry DOI: 10.7270/Q2DF6S86
					More data for this Ligand-Target Pair